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Writer's pictureThe San Juan Daily Star

How science went to the dogs (and cats)


Max, a 2-year-old German shepherd, Belgian Malinois and husky mix, photographed in Greenlake Park in Seattle on June 14, 2024. Scientists around the world are peering deep into the bodies and minds of cats and dogs, hoping to learn more about how they wriggled their way into our lives, how they experience the world and how to keep them living in it longer. (M. Scott Brauer/The New York Times)


By SETH KUGEL


Every dog has its day, and July 14, 2004, belonged to a boxer named Tasha. On that date, the National Institutes of Health announced that the barrel-chested, generously jowled canine had become the first dog to have her complete genome sequenced. “And everything has kind of exploded since then,” said Elaine Ostrander, a canine genomics expert at the National Human Genome Research Institute and who was part of the research team.


In the 20 years since, geneticists have fallen hard for our canine companions, sequencing thousands upon thousands of dogs, including pedigreed purebreds, mysterious mutts, highly trained working dogs, free-ranging village dogs and even ancient canine remains.


Research on canine cognition and behavior has taken off, too. “Now, dog posters are taking up half of an animal behavior conference,” said Monique Udell, who directs the human-animal interaction lab at Oregon State University. “And we’re starting to see cat research following that same trend.”


Just a few decades ago, many researchers considered pets to be deeply unserious subjects. (“I didn’t want to study dogs,” said Alexandra Horowitz, who has since become a prominent researcher in the field of canine cognition.) Today, companion animals are absolutely in vogue. Scientists around the world are peering deep into the bodies and minds of cats and dogs, hoping to learn more about how they wriggled their way into our lives, how they experience the world and how to keep them living in it longer. It’s a shift that some experts say is long overdue.


“We have a responsibility to deeply understand these animals if we’re going to live with them,” Udell said. “We also have this great potential to learn a lot about them and a lot about ourselves in the process.”


Pet projects


For geneticists, dogs and cats are both rich subjects, given their long, close history with humans and their susceptibility to many of the same diseases, from cancer to diabetes.


Dogs have been an especially appealing target. Intense human selection, especially over the past few centuries, has created a staggeringly diverse collection of canines, from Chihuahuas to Great Danes, and hundreds of reproductively isolated breeds, which often suffer from high rates of disease.


In the 2000s, scientists identified the genetic underpinnings of a variety of canine traits, including curly coats and bobbed tails. They pinpointed mutations that could explain why white boxers were prone to deafness. And they found that corgis, basset hounds and dachshunds owe their stubby legs to a genetic aberration in a family of genes that also regulates bone development in humans.


These early studies “highlighted both the potential that we could learn from dogs, but also that we were going to need bigger sample sizes to do it really well,” said Elinor Karlsson, a geneticist at UMass Chan Medical School and the Broad Institute. So, researchers began creating large citizen science projects, seeking DNA samples and data from dogs across the United States.


Pet owners rose to the challenge. The Golden Retriever Lifetime Study, which began recruiting in 2012, has been following more than 3,000 dogs in an effort to identify genetic and environmental risk factors for cancer, which is especially common in the breed. Since 2019, the Dog Aging Project, a long-term study of health and longevity, has enrolled nearly 50,000 dogs.


Karlsson’s own project, Darwin’s Dogs, is at 44,000 canines and counting. (About 4,000 have had their genomes sequenced.) Researchers are mining the data for clues about bone cancer, compulsive behavior and other traits. Among the early findings: Although many behavioral traits, such as sociability and trainability, are heritable, they are widely distributed across the canine kingdom, and breed is a poor predictor of an individual dog’s personality.


This past spring, Karlsson unveiled a much-anticipated expansion: Darwin’s Cats. “I’m a total cat person — have never owned a dog,” she said. Later, in an email, she added, “I’d love to know if ‘cat sleeps on your head’ is influenced by genetics.”


Dog days of psychology


Several decades ago, scientists seeking to decipher animal minds typically studied wild, big-brained creatures, such as great apes and cetaceans, or laboratory stalwarts, such as rodents and birds. Those animals that napped on our couches? “People really were not thinking about dogs as true animals,” said Horowitz, a canine cognition researcher at Barnard College. “Because they were in our homes, and they’re domesticated — like, they were so adulterated that they weren’t interesting.”


But in the late 1990s and early 2000s, two research teams reported that dogs were gifted at interpreting human cues, successfully following human pointing gestures and eye gazes to locate hidden food. On these tasks, they outperformed wolves raised by people and even, in some cases, great apes. The studies suggested that dogs possessed sophisticated forms of social cognition, and researchers sat up in attention.


Additional research has since added detail and nuance to those early studies, highlighting the capabilities and the limitations of the canine mind. The data generally confirm that dogs are skilled at social tasks and highly attuned to human cues. But the science also suggests that we are sometimes too eager to project our own experiences onto dogs. When dogs display what many people describe as a “guilty look” — averting their eyes and slinking away from their owners, perhaps — they are probably responding to being scolded, not feeling regret over a misdeed, Horowitz found.


The field blossomed, in part, because dogs were cooperative, convenient and affordable subjects. Why trek into the wild or house hundreds of animals in a lab? Canine cognitive scientists could simply borrow the approach of developmental psychologists.


“People who do developmental psychology don’t have labs full of 12-month-olds,” said Evan MacLean, director of the Arizona Canine Cognition Center at the University of Arizona. “They have phone numbers of parents. We have the phone numbers of dog parents.”


Cats as catch can


Until recently, scientists took little interest in the social cognition of cats, which did not descend from highly social animals and were often viewed as aloof. But emerging research suggests that some cats, at least, have plenty of social acumen, including the ability to pick up on human emotions and follow human gazes.


Perhaps our perception of cats as independent (and sometimes intransigent) is a self-fulfilling prophecy, Udell said. She noted that kittens are not typically given the same socialization and training opportunities that puppies are. Maybe those enrichment opportunities would help cats show off exactly what they are capable of.


Dogs and cats have become supremely successful at navigating the human world, but deepening our relationships with them might require understanding them on their own terms.

“They have their own drives and desires and needs and ways of understanding the world,” said Clive Wynne, a canine-behavior expert at Arizona State University. “And it’s a beautiful miracle that their way of understanding the world, especially the social world, and our way of understanding the world can be melded together into this really very beautiful partnership.”

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